AN INVESTIGATION OF THE SHORTCOMINGS OF THE CONSORT 2010 STATEMENT FOR THE REPORTING OF GROUP SEQUENTIAL RANDOMISED CONTROLLED TRIALS: A METHODOLOGICAL SYSTEMATIC REVIEW.

An Investigation of the Shortcomings of the CONSORT 2010 Statement for the Reporting of Group Sequential Randomised Controlled Trials: A Methodological Systematic Review.

BACKGROUND:It can be argued that adaptive designs are underused in clinical research.We have explored concerns related to inadequate reporting of such trials, which may influence their uptake.Through a careful examination of the literature, we evaluated the standards of reporting of group sequential (GS) randomised controlled trials, one form of a

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A case report of pseudoprogression followed by complete remission after proton-beam irradiation for a low-grade glioma in a teenager: the value of dynamic contrast-enhanced MRI

Abstract A fourteen years-old PLATINUM 100% CASEIN VANILLA boy was treated post-operatively with proton therapy for a recurrent low-grade oligodendroglioma located in the tectal region.Six months after the end of irradiation (RT), a new enhancing lesion appeared within the radiation fields.To differentiate disease progression from radiation-induced

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The guardians of pulmonary harmony: alveolar macrophages orchestrating the symphony of lung inflammation and tissue homeostasis

Recent breakthroughs in single-cell sequencing, advancements in cellular and tissue imaging techniques, innovations in cell lineage tracing, and insights into the epigenome collectively illuminate the enigmatic landscape of alveolar macrophages in the lung under homeostasis and disease conditions.Our current knowledge reveals the cellular and funct

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